Psychosis

Author: Lawrence Dautel

Examination of Resting State Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging Techniques in Psychosis

INRODUCTION

This is a retrospective study investigating novel Resting State Functional Magnetic Resonance Imaging (rsfMRI) and Diffusion Tensor Imaging (DTI) analysis methods to assess psychosis. Proprietary software originally developed to study the effects of brain tumors on white matter tracts will be applied to study psychosis patients. DTI metrics are useful tools for analyzing the integrity of white matter. Comparisons between axial and radial diffusivity measurements can be useful for analyzing lesions. Advanced Magnetic resonance imaging (MRI) techniques such as diffusion tensor imaging (DTI) and resting state functional MRI (rsfMRI) have offered noninvasive means to study the changes of brain network architecture related PTE. DTI measures structural connectivity which is related to white matter tracks in the brain where as rsfMRI infers functional connectivity by measure the correlation of the blood flow patterns between two regions of the brain